What is Semaglutide?

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What is Semaglutide?

As we step into the New Year, many find their resolutions revolving around health and wellness goals, specifically weight loss. One breakthrough gaining attention when considering weight loss options is semaglutide.

Initially designed for diabetes management, semaglutide has now proven effective in weight loss, even for non-diabetic individuals. What is semaglutide for weight loss in non diabetics, though? What exactly is semaglutide in general?

What is Semaglutide?

Semaglutide is a glucagon-like peptide-1 receptor agonist, and was primarily developed for managing diabetes. GLP-1 receptors play an important role in controlling blood sugar and appetite during insulin secretion. Basically, they help regulate insulin, contributing to the feeling of fullness that occurs after eating. Semaglutide is a substitute for these receptors. The feeling of fullness plays a significant role in potential for weight loss in non-diabetic individuals. This dual functionality is one of the major benefits of semaglutide.

Ozempic often comes up in the discussion of semaglutide and alternative weight loss methods. Specifically, the question, ‘is semaglutide the same as Ozempic?’ Essentially, yes. “Semaglutide” is the generic drug name for the brands Ozempic, Wegovy, and Mounjaro. However, the key difference is they have a different dosing schedule. 

Suitable Candidates for Semaglutide

If you’re wondering how to get semaglutide, it should first be noted that semaglutide would not be recommended or suitable for those just looking to lose a few pounds. Semaglutide for weight loss purposes is typically only considered for individuals who struggle with obesity or excess weight and have been unsuccessful in achieving significant results through conventional methods like diet and exercise alone. Ideal candidates are often those with a body mass index (BMI) of 30 or higher, although lower BMIs may be considered based on individual health factors. 

Candidates may also include individuals with obesity-related comorbidities, such as hypertension or type 2 diabetes, seeking something that will address both weight management and associated health issues. Before considering the semaglutide route, it's crucial to consult with healthcare professionals who can assess their medical history, lifestyle, and overall health. They will always be the best resource to determine the suitability for those wondering how to get semaglutide for weight loss.

Duration and Speed of Semaglutide

Some understandably common questions surrounding semaglutide in weight loss are, how fast do you lose weight on semaglutide? How long do you stay on semaglutide for weight loss? How long does it take for semaglutide to work? How long does semaglutide stay in your system?

The speed at which semaglutide works for weight loss varies among individuals, but many users may observe initial effects within the first few weeks of treatment. It's important to note that the process is gradual, and individual responses can differ. Some individuals may experience noticeable weight loss within the first week, while others may take a bit longer. 

The sustained effectiveness of semaglutide is a key advantage, as it provides ongoing support for weight management. Semaglutide offers a continuing impact, and its benefits often persist as long as the medication is used as directed. This extended use makes semaglutide a promising option for individuals seeking a long-term solution to weight loss.

Potential Side Effects of Semaglutide

While semaglutide has demonstrated effectiveness in weight loss, it is important to be aware of potential side effects associated with its use. Common side effects include gastrointestinal symptoms such as nausea, vomiting, diarrhea, and abdominal discomfort, especially during the initial phases of treatment. These symptoms may gradually subside as the body adjusts to the medication. 

Additionally, a common question is, does semaglutide make you tired? There is indeed a possibility of experiencing semaglutide fatigue, which is generally temporary. Rare but more serious side effects may include pancreatitis and changes in kidney function. You should always discuss medical history and any pre-existing conditions with healthcare professionals. Regular monitoring and open communication are essential to promptly address any side effects and ensure a safe and effective weight loss journey with semaglutide.

Semaglutide Tablets vs Injection

Available in both tablet and injectable forms, individuals can choose the method that best suits their needs. Semaglutide tablets are a convenient oral option, allowing easy incorporation into daily routine. On the other hand, injectable semaglutide, administered via a prefilled pen, offers a subcutaneous injection that can be self-administered. The choice between tablets and injections often depends on individual preferences, comfort levels, and considerations such as needle aversion. If you’ve chosen injections and are wondering how to inject semaglutide or the best place to inject semaglutide, those would best be answered by your healthcare professional. 


As we embrace the New Year, semaglutide emerges as a potential option for weight loss for those that have not found success in conventional ways. Navigating whether it's a suitable option, its administration, dosage, and lifestyle considerations, will require insight and collaboration with healthcare professionals. 

Regenerative and Sports Medicine clinic is a great first contact for those wanting professional opinions on semaglutide. Dr. Rand McClain has been prescribing semaglutide for diabetes and weight loss since the beginning of 2022 and can speak to its considerable improvements in health.